ML1 [FBbt_00052137]
Optic lobe neuron that has its soma in the anterior medulla cell body rind, multicolumnar dendritic innervation of the medulla, and an axon that reaches the anterior lobula without passing through the second optic chiasm (Kind et al., 2021). Its dendritic arborization spans approximately 20 optic columns, ramifying in layers M1-4 and M8 from vertical processes (Kind et al., 2021). It receives synaptic input from R8 photoreceptors, mainly in pale optic columns (Kind et al., 2021). Its axon leaves the distal medulla and travels anteriorly to reach layer 6 of the lobula, where it has postsynapses in a few columns (Kind et al., 2021; Nern et al., 2025). In a subpopulation of these cells its axon also innervates the central brain (Kind et al., 2021). It is predicted to be cholinergic (Eckstein et al., 2024; Nern et al., 2025). There are around 45 of these cells per optic lobe (Kind et al., 2021; Nern et al., 2025).
ML1
ID: FBbt_00052137
Adult Cholinergic Nervous system Visual system
Optic lobe neuron that has its soma in the anterior medulla cell body rind, multicolumnar dendritic innervation of the medulla, and an axon that reaches the anterior lobula without passing through the second optic chiasm (Kind et al., 2021). Its dendritic arborization spans approximately 20 optic columns, ramifying in layers M1-4 and M8 from vertical processes (Kind et al., 2021). It receives synaptic input from R8 photoreceptors, mainly in pale optic columns (Kind et al., 2021). Its axon leaves the distal medulla and travels anteriorly to reach layer 6 of the lobula, where it has postsynapses in a few columns (Kind et al., 2021; Nern et al., 2025). In a subpopulation of these cells its axon also innervates the central brain (Kind et al., 2021). It is predicted to be cholinergic (Eckstein et al., 2024; Nern et al., 2025). There are around 45 of these cells per optic lobe (Kind et al., 2021; Nern et al., 2025).
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## Classification
Relationships
Alternative Names
| Synonym |
Scope |
Reference |
| MeLo1 |
exact synonym |
Berg et al., 2025 |
| adult medulla-lobula neuron MeLo1 |
exact synonym |
Nern et al., 2025 |
| MeLo1 |
exact synonym |
Nern et al., 2025 |
| medulla-to-lobula cell ML1 |
exact synonym |
Kind et al., 2021 |
| adult ML1 neuron |
exact synonym |
Kind et al., 2021 |
| ML1 |
exact synonym |
Kind et al., 2021 |
| MLt1 |
exact synonym |
Bates et al., 2025 |
| MLt1 |
exact synonym |
Schlegel et al., 2024 |
| CB3833 |
exact synonym |
Schlegel et al., 2024 |
| MLt1 |
exact synonym |
Matsliah et al., 2024 |
| amacrine-like cell |
related synonym |
Kind et al., 2021 |
| MeLo1 |
exact synonym |
|
| adult CB3833 neuron |
exact synonym |
Schlegel et al., 2024 |
| amacrine-like cell |
related synonym |
Gao et al., 2008 |
List all available images of ML1 (323 total)
| Thumbnail |
Name |
Tags |
 |
MeLo1_L (MaleCNS:220992) |
Nervous_system, Visual_system, Adult, Cholinergic |
 |
MeLo1_L (MaleCNS:35391) |
Nervous_system, Visual_system, Adult, Cholinergic |
 |
MeLo1_R (MaleCNS:27669) |
Nervous_system, Adult, Visual_system, Cholinergic |
 |
MeLo1_R (MaleCNS:35445) |
Nervous_system, Visual_system, Adult, Cholinergic |
 |
MeLo1_R (MaleCNS:39072) |
Nervous_system, Visual_system, Adult, Cholinergic |
View all 323 results in VFB →
Expression patterns overlapping ML1 (1 total)
View all 1 results in VFB →
Transgene expression in ML1 (1 total)
View all 1 results in VFB →
Downstream connectivity classes for ML1 (448 total)
View all 448 results in VFB →
Upstream connectivity classes for ML1 (233 total)
View all 233 results in VFB →